There is a factory service bulletin for the 2000 Toyota Camry:
2000 Toyota Camry Factory Service Bulleting OBDII Code P0300 Code
Check the 'Possible Causes' listed above. Visually inspect the related wiring harness and connectors. Check for damaged components and look for broken, bent, pushed out, or corroded connector pins.
The cost to diagnose the P0300 2000 Toyota Camry code is 1.0 hour of labor. The diagnosis time and labor rates at auto repair shops vary depending on the location, make and model of the vehicle, and even the engine type. Most auto repair shops charge between $75 and $150 per hour.
The control module monitors the crankshaft speed and has detected a misfire condition
When a misfire occurs, engine speed will fluctuate. If the engine speed fluctuates enough to cause the Crankshaft Position (CKP) sensor signal to vary, the Engine Control Module (ECM) can determine that a misfire is occurring.
Need more information on how to fix the P0300 2000 Toyota Camry code? Get Access to Factory Service Manuals
Get the P0300 2000 Toyota Camry code diagnosed by a professional: Find a repair shop in your area